Zhang Chengping, Gu Changhai, Wang Yumin （Institute of Liver Diseases, General Hospital of Beijing Military Region , Beijing 100700, China）
Abstract:
Objective On the purpose of further estimation of therapeutic effects on chronic severe viral hepatitis with PGE1 .Methods we observed the plasma levels of endotoxin,TNF-α,PGE2 and changes of other clinical features before and after PGE1 treatment for 31 patients of chronic sevre viral hepatitis with PGE1. Results The decreased plasma levels of endotoxin, TNF-α, SB, ALT and the increased plasma level of PGE2 , PTa were achieved after treatment. Conclusion Our studies suggested that PGE1 were effective for chronic severe viral hepatitis and corrected remarkedly pathological disturbance , it can act as a effective drug in comprehensive treatment for chronic severe viral hepatitis.[著者文摘]
Key words:
Prostaglandin E1 ; Tumor necrosis factor-a ; Endotoxin ; Severe viral Hepatitis
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