Human liver is the largest gland is the largest organ substantive liver are mainly located in the right upper abdomen and ribs quarter (Figure 1). My adult liver weight, 1230-1450g for men, women 1100-1300g, or about the weight 1/40-1/50. In fetuses and newborns, the liver relatively large size, weight up to 1 / 20. My liver diameter, wide diameter 25X15cm.
Because the liver is rich in blood supply, so the liver was red brown, soft and crisp. Liver subguadratic round blunt thick, thin with extreme narrow wedge, on the two sides, after about four margin. Carina above affixed to the diaphragm by the sickle-shaped ligament is divided into left and right two leaves; Below slightly concave, near the adjacent organs, the surface is slightly H-shaped groove around longitudinal and transverse grooves right groove traveling deep ditch before the round ligament of the liver and right vertical groove wide and shallow, with the front of the gallbladder fossa accommodate gallbladder, a rear cavity under static Waterloo clock through the inferior vena cava. Wang groove with portal vein, liver artery, the liver, nerve and lymphatic called hepatic portal access. Most of the liver in the right quarter of the ribs and abdomen, small parts in the left quarter of his ribs. Liver on the same sector and the dome diaphragm, liver, adult community in general clavicle centerline cross rib in the five level. Liver coverage for the majority of Legong only in the left upper abdomen, between the arch again exposed 3-5cm, and pasted on anterior abdominal Therefore, normal again at the margin of the liver difficult to hit bottomline. If the location liver sector normal adult again if the margin of the liver hit, compared with pathologic hepatomegaly. Children below the liver can lower bound Legong. Because liver by coronary ligament above even the diaphragm, so when breathing, the diaphragm with liver can campaign all mobile, received up to 2-3cm. The right upper abdominal and rib quarter combat areas such as violence or rib fractures, which can lead to liver laceration (Figure 2).
Liver adjacent organs above the left lobe adjacent diaphragmatic pericardium and the heart. The right lobe right above diaphragm neighboring pleural cavity and right lung, liver abscess sometimes diaphragm surface erosion and spread to the right pleural cavity and right lung. After the medial margin of the right lobe adjacent esophagus, stomach left anterior wall of the following contacts, the contact side of the pylorus, right below the front of the right colon contact Qu, near the central portal adjacent to the duodenum. Behind contact kidney and adrenal (Figure 3).
The intrahepatic liver and intrahepatic vascular based fissures can be divided into five-and fourth: the left in the leaves, left, leaves, leaf right anterior, posterior lobe of the right caudate lobe; Left outer leaves are divided into outer leaves left on the next paragraph, right after, right after the leaves are divided into upper and under. Many of the liver was fixed in the peritoneal ligaments, the liver surface was coated gray liver wrapped. The liver's blood supply 3 / 4 from the portal vein, 1 / 4 from the hepatic artery. The end of the portal vein in the liver sinus expansion, it is Hepatic Lobules blood circulation within the pipeline. Hepatic arterial blood from the heart, the main supply of oxygen, the portal venous blood collection gastrointestinal main supply nutrition.
People in the liver of the role played by
Liver - is the human body's largest digestive gland. In vivo metabolism is at the center. According to estimates, in the liver occurred in a chemical reaction more than 500 species, experimental proof, animal liver completely removed even after the corresponding treatment, most can only survive more than 50 hours. This shows that the liver is a life-sustaining activities essential to vital organs. The liver blood flow is much richer in cardiac output of about 1 / 4. Every minute into the liver blood flow for the 1000-1200ml. Liver main function is the decomposition of sugar, glycogen storage; Participation in protein, fat, vitamins, hormone metabolism; Detoxification; Secreting bile; Phagocytosis, defense function; Manufacturing coagulation factor; Water regulation of blood volume and electrolyte balance; Such heat. Still in the embryonic period liver hematopoiesis.
1. Hepatic bile secretion: liver cells can continue to generate bile acid and bile secretion of bile in the digestive process of the fat in the intestine for digestion and absorption within. Every day 600-1100 of bile duct transported to the gallbladder. Gallbladder bile from the concentration and emission features.
2. Liver and glucose metabolism: monosaccharide absorbed by the intestinal mucosa, liver by the portal vein arrived in liver glycogen and into storage. General adult liver glycogen about 100g of the original, just enough for a 24-hour fasting purposes. The glycogen concentration in blood glucose regulation in order to maintain its stability, play an important role. When labor, hunger, fever, massive consumption of glucose, liver cells and liver glycogen can decomposition of glucose into the blood circulation, so often prevalent blood glucose changes.
3. Liver and protein metabolism: the gastrointestinal absorption of amino acids in protein synthesis within the liver, deaminase, and ammonia to the role of protein synthesis in the blood circulation need for systemic organs. Plasma protein synthesis of the liver is the main place, as the plasma protein can be used as protein in the various organizations of the update, and therefore the liver plasma protein synthesis of the role of the protein metabolism of the body are important. Amino acid metabolism in the liver to produce ammonia synthesis of urea, excreted by the kidneys. So liver disease and reduce the plasma protein can be increased ammonia.
4. Liver and fat metabolism: Fatty liver is the transport hub. After the digestion and absorption of fat into the liver, subsequent changes to the storage of body fat. Hunger, storage of body fat can first be transported to the liver and then proceed to decomposition. In the liver, can be neutral fat hydrolysis of glycerol and fatty acids, the reaction can be accelerated hepatic lipase, glycerol can be used glucose metabolic pathways, and fatty acid oxidation to be completely carbon dioxide and water. In vivo liver or fatty acids, cholesterol, phospholipids one of the main organs. When fat metabolism disorder, fat accumulation in the liver can be a fatty liver.
5. Vitamin metabolism: liver can be stored fat-soluble vitamins, 95% of the human vitamin A is stored in the liver, liver vitamin C, D, E, K, B1, B6, B12, niacin, folic acid and other vitamins and metabolic storage sites.
6. Hormones: under normal circumstances hormones in the blood have to maintain a certain level of surplus with the loss of activity of the liver. When 28,000, estrogen inactivation possible obstacles, aldehyde steroids and anti-diuretic hormone inactivated obstacles.
7. Detoxification Function: In the process of metabolism, portal collected from abdominal blood flow to the blood of harmful substances and microbial resistance of the material will be in liver detoxification and removal. Liver detoxification four main ways: (a) Chemical Methods: If oxidation, reduction, decomposition, and the combination of deoxy role. (2) secretion: some heavy metals such as mercury, and bacteria from the gut, with the secretion of bile from. (3) reserves; (4) phagocytosis. Human liver is the main organ detoxification, it may protect the body against damage to a non-toxic chemicals or solubility of the material, with the bile or urine from the break.
8. Defense mechanism: the liver is the largest reticuloendothelial system phagocytosis. Hepatic venous sinus cortex contains a large number of Kupffer cells, a strong phagocytosis, in the portal vein 99% of the hepatic venous sinus bacteria were engulfed. Therefore, the filtration liver extremely clear the importance of the role.
9. Regulation of blood circulation: normal hepatic venous sinus can store a certain amount of blood, bleeding in the body, from liver sinus emit more blood, peripheral circulation volume to compensate for the shortcomings.
10. Manufacturing coagulation factor: the liver is the body's main various coagulation factor sites, the body of 12 coagulation factor, which four species are synthesized in liver. Liver disease can cause clotting factor causing the lack of clotting time and bleeding tendency.
11. Heat generation: water and electrolyte balance of the regulation, are involved in the liver. Quiet, the main body of calories provided by the body organs. In the labor movement and at a time when the major organs of the muscle. In all offal, the liver is the organ in vivo metabolism strong, quiet, liver blood flow temperature 0.4-0.8 degrees Celsius higher than the aorta, the greater its heat production.
12. Liver regeneration capacities: animal experiments proved that when the liver was excised 70-80%, that is not obvious physiological disorder. But remnants of the liver in three weeks to eight weeks, as long as the original size. This shows that the regeneration of liver function. |